Autoimmune disorders result when the immune system develops a strong protective reaction against any one of the body's internal components as though they were harmful. Common autoimmune diseases fall into two categories: systemic autoimmune diseases where multiple organs or tissues are affected; and localized autoimmune diseases where only one organ or tissue is affected. There are many causes of autoimmunity including: genetic weakness, viral, bacterial and fungal infections, excessive stress, drugs, etc. These conditions cause the immune system to release chemicals called cytokines which cause swelling and inflammation of the organs, and sometimes they also cause permanent damage to the affected cells. The consequence is that some of the cells become chronic or permanent memory makers for the autoimmune disorder causing them to become sensitized to the stimuli that the sufferer is unable to control. This creates a domino effect: once the inflammatory response has started, it is very difficult to halt because the immune cells and tissues have become permanently memory makers. The blood test results suggest that a large number of these immune cells and tissues are permanently damaged in autoimmune diseases. The test results also show that the number of antibodies produced by the cells is different from normal. The antibodies normally make antibodies to fight infection, but in this case they have become memory makers that cause chronic inflammation. Another name for this condition is sepsis (infection) because the first attack occurs normally in the digestive system. In sepsis, too much fluid accumulates in the blood. As the fluid accumulates, the presence of bacteria or viruses in the blood increases. When the fluid reaches a critical level, the symptoms like nausea, fever, chills, etc. Autoimmune disorders can be inherited or acquired. Some examples of autoimmune diseases include Lupus, systemic Lupus erythematosus (SLE), fibromyalgia, hepatitis B, childhood diseases like Addison's disease, etc. In most cases, these autoimmune disorders start to develop during childhood. When the body experiences an exaggerated immune system activity, the result is the activation of the inflammatory response. This overactive immune activity damages the blood vessels and disrupts the normal blood flow to the entire body. When this happens, the body experiences various symptoms such as joint stiffness, pain, fever, etc. Most people suffering from autoimmune diseases often feel that something is seriously wrong with them. It is important to know that any part of the body, including the skin, is subject to these disorders. When the blood vessels are damaged, the blood supply to any part of the body is affected.